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pentobarbital will decrease the level or impact of venetoclax by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases outcomes of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Coadministration of CYP3A4 inducers could reduce sufentanil levels and efficacy, p